I was thinking a lot about this and trying to think of the better Pitt player offensive performances.
Artis had a monster 40+ game. Sam Young was lights out against OSU in the NCAA Tournament his senior year; he had some other similar games too. Lamar Patterson lit a few teams up his senior year. That is about it over the past 20 years or so. It was a great game for him.
I'd say this was the second best Panther game at the Pete, putting only the Sam Young 31 point performance against UConn in 2009 ahead of it. I give that one the nod because it was on the biggest possible stage against a Top 5 opponent. But Burton's 14-17 makes a great case for him.
Some of others of this millennium include (not all at the Pete):
Trey McGowens 33 against Louisville (31 in regulation).
Artis' 43 against L-ville that you mentioned (although I tend to downgrade this performance because Jamel scored 30 of his points after the Panthers went behind by 26 points)
Sam's 32 against OK State in the NCAA tourney that you mentioned.
Mike Young's 30 against Marquette in the 2K Classic.
Mark McCarroll's 26 against Georgia (11-12 shooting).
Chevy's 29/12 performance against UConn in 2005 (25 in the second half to lead to Panthers to victory after a 13 point second half deficit).
Blair's 22 point, 23 rebounds at UConn in 2009.
Brandin Knight's 20 point, 14 assist performance against Miami in the 2002 BET.
Two of Lamar's best included his 28-7-7 against Maryland and his 30 against Clemson to pull the win in OT (both in 2014).