There's a ~50 mile stretch of road on I81 around JMU that is, for my money, the worst stretch of road in the country. It's all 2 lane mountain road and extremely tractor trailer heavy. And those dudes don't give AF and will ride the left lane and cut you off like it's nothing. If you're coming in Friday and don't mind the possibly of getting stuck in a 90-120 minute accident delay (I've done the I81 trip all the way from NC to PA probably 10 times), which I've seen probably 7/10 times, usually heading north, then I agree, it's a pretty scenic ride. Just know that with the tractor trailers and hayseed 1980 pickup truck drivers in western Virginia, it can be a very stressful journey.
That said, I hate I95 around DC, so I always take I77 to I81 to get back to the PA turnpike.