Ewwww - Ignore some of the bizarrly negative + completely incorrect "analysis" in terms of the question. It's one I considered as well last year and this year --- Pitt and Stanford --- with both being the rare Under Center, Huddle-Up smash mouth offenses.
Stanford last year was 9-3 in the Pac-12, and won a very hard-fought Sun Bowl game Vs. North Carolina that came down the final minutes. If Mitch Trubisky doesn't throw a really, really bad Pick-6 in that game I think North Carolina wins.
Pitt's offense is just as good overall, and if Max Browne plays like an NFL draft pick I would say he gives Pitt's offense a clear edge (Keller Chryst is okay, not an NFL level QB) --- but yes, Stanford's Defense is just much deeper, experienced, and in-tune together as of now than Pitt's totally green and young (albeit very TALENTED!) defense. Stanford's defense last year and this year is the tough, experienced, and deep crew that Pitt is hoping to become the next few seasons.
Some of the above posts insisting that "Stanford wins by 3 TD's" is borderline-vitriol and just silly.
Pitt and Stanford, this year AND last year I would put Stanford as a 6 point favorite.